MONDAY, June 17, 2024 (HealthDay News) — Bariatric surgery significantly reduces the conversion of prediabetes to type 2 diabetes, according to a study presented at the annual meeting of the American Society for Metabolic and Bariatric Surgery, held June 9-13 in San Diego.
John Nguyen Le, MD, of Geisinger Medical Center in Danville, Pennsylvania, and colleagues evaluated conversion rates from prediabetes to type 2 diabetes after bariatric surgery compared with conversion rates seen in nonsurgical cohorts. The analysis included 1,326 obese cases of prediabetes and a propensity-matched nonsurgical control group from a primary care cohort.
The researchers found that the rates of conversion to diabetes were 1.8, 3.3, and 6.7 percent at 5, 10, and 15 years after surgery, respectively. In the non-surgery control group, the rates of conversion to diabetes were significantly higher at all time points (31.1, 51.4, and 68.7 percent, respectively; hazard ratio: 19.8). Compared with patients who underwent Roux-en-Y gastric bypass, patients who underwent sleeve gastrectomy were more likely to convert to type 2 diabetes (hazard ratio: 4.01).
“This is the first study to analyze the long-term effects of metabolic and bariatric surgery on the potential progression of prediabetes, and the effects are significant and long-lasting,” co-author David Parker, M.D., also of Geisinger Medical Center, said in a statement. “We demonstrate that metabolic surgery can both prevent and treat diabetes.”
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