- Approximately 12% of women worldwide have a detectable HPV infection, There is currently no cure.
- High-risk types of HPV are associated with an increased risk of many cancers.
- Researchers found evidence suggesting that women with high-risk strains of HPV have a four times higher risk of dying from cardiovascular disease.
Researchers estimate that approximately 12% of women worldwide have detectable human papillomavirus (HPV) infection.
HPV is
Men can also be infected with HPV.
There are currently no treatments to treat HPV. The majority of people infected with HPV
However, in some formats,
Now, researchers at Sungkyunkwan University School of Medicine in Seoul, South Korea, have found evidence suggesting that women with high-risk HPV types are four times more likely to die from cardiovascular disease.
This research recently european heart journal.
The study was inspired by a growing body of evidence, said Seungho Ryu, Ph.D., professor at the Cohort Research Center, Gangbuk Samsung Hospital Total Healthcare Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, and co-lead author of the study. It is said that Study of the potential association between high-risk strains of HPV and cardiovascular disease.
“Given the widespread prevalence of HPV and its well-established association with certain cancers, our goal is to understand the broader health effects of HPV, particularly its role in cardiovascular mortality. “We investigated this in detail,” Dr. Liu said. Today’s medical news.
“This study sought to uncover new modifiable risk factors for heart disease, targeting gaps that cannot be explained by traditional risk factors such as smoking, high cholesterol, hypertension, and diabetes. Despite great advances in the management of heart disease, heart disease remains the leading cause of death.
— Dr. Ryu Seungho
“Of note, traditional risk factors do not explain all cases of heart disease. Approximately 20% also occur in people without these diseases, making it important to investigate additional variable risk factors. “It emphasizes the importance of doing so,” he said.
This is not the first study to examine the link between HPV and heart disease. A study published in June 2019 found that HPV may be associated with the following symptoms:
And in a study published in March 2023,
For the study, Dr. Ryu and his team analyzed data from more than 163,000 young and middle-aged Korean women who had no diagnosis of cardiovascular disease at the start of the study. Study participants underwent a number of health screening tests, including cervical screening for 13 high-risk HPV strains.
“Our study focused on 13 high-risk HPV strains, including:
“High-risk HPV strains have the ability to interact with and destroy tumor suppressor proteins in cells, causing cellular changes that lead to malignancies, particularly cervical cancer,” he continued. “Additionally, high-risk HPV strains, particularly HPV 16 and HPV 18, may be involved in cardiovascular disease.”
Dr. Ryu said high-risk HPV may increase the risk of death from cardiovascular disease through mechanisms that involve direct effects on chronic inflammation and atherosclerosis.
“The presence of high-risk HPV strains is associated with systemic inflammation, which is a key factor in the development of atherosclerotic cardiovascular disease,” he continued. “This suggests that HPV infection may contribute to cardiovascular disease progression by exacerbating the inflammatory process.”
During the study, participants were followed for up to 17 years, during which time they underwent regular health check-ups.
According to researchers, the risk of dying from cardiovascular disease in young, healthy women is about 9.1 in 100,000.
When accounting for other factors known to increase the risk of heart disease, such as obesity, smoking, diabetes, and high blood pressure, women with high-risk HPV had a 3.91 times higher risk of artery blockage and a 3.74 times higher risk. It was discovered by scientists. Compared with women without high-risk HPV infection, they had a 5.86-fold increased risk of death from cardiovascular disease and a 5.86-fold increased risk of death from stroke.
The researchers also reported that these risks were even higher in study participants who had both high-risk HPV infection and obesity.
“Our findings show a strong association between high-risk HPV infection and increased cardiovascular disease (CVD) mortality, particularly atherosclerotic cardiovascular disease. To understand the systemic impact of this virus, primarily known for its role in causing cervical cancer and other cancers, by elucidating the significant impact of HPV on cardiovascular mortality. A new path will open up.”
— Dr. Ryu Seungho
“While our study provides important insights into the association between high-risk HPV and cardiovascular mortality, it also highlights several areas where further research is needed,” said Dr. Ryu. .
“Limitations regarding demographic focus and lack of data on vaccination status and specific HPV genotypes point to the need for more comprehensive, long-term studies. These future studies will “We should aim to include a wider range of people, including men, to fully understand the impact on cardiovascular health,” he added.
After reviewing the study, Dr. Nicole Weinberg, a board-certified cardiologist at Providence St. John’s Health Center in Santa Monica, Calif., said: MNT This study is part of a current trend to investigate chronic inflammation and focus on what it is and how it can be treated.
“Something like HPV that we know is something that can be identified and treated in a certain capacity, and as a clinical cardiologist who sees a lot of patients, we know that it’s the cause of chronic inflammation in our patients. “It’s very exciting to know that we can identify and then potentially treat,” Dr. Weinberg said.
MNT I also spoke with G. Thomas Lewis, M.D., a board-certified obstetrician and chief obstetrician and gynecologist at MemorialCare Orange Coast Medical Center in Fountain Valley, California, who said that HPV and He said he was highly skeptical about the link to vascular disease.
“We don’t know whether we can prove an association between HPV and cardiovascular disease based on just one study in this population. Further research is needed,” Dr. Lewis continued. “This study was conducted in South Korea, so the population is homogeneous. Whenever we deal with studies that involve homogeneous populations, we want to have as much diversity in the study as possible, so we You’ll want to expand your research.”
“We would like to be able to reproduce the data for people with a BMI below 30 who are high-risk HPV positive. [t]For me, that might be more beneficial,” he added.
